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NPR
Shots - Health News
Scientists at Pfizer's research and development laboratories in Groton, Conn., worked on the COVID-19 pill called Paxlovid.

How Pfizer developed a COVID pill in record time

Dec 03, 2021
Pfizer researchers looking for a drug to treat SARS found clues that gave the company a head start in its quest for a pill to treat COVID-19, including the omicron variant.
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NPR
Shots - Health News
A COVID-19 antiviral pill called molnupiravir from Merck and Ridgeback Biotherapeutics is being considered by the Food and Drug Administration for emergency use in the coronavirus pandemic.

An FDA panel supports Merck COVID drug in mixed vote

Nov 30, 2021
If the Food and Drug Administration authorizes use of the drug, called molnupiravir, it would be the first oral COVID-19 treatment that could be taken at home.
NPR
Shots - Health News
Portrait of Phillip Lyn taken by his spouse, Kurt Rehwinkel, outside their home in St. Louis.

For Those Facing Alzheimer's, A Controversial Drug Offers Hope

Jun 15, 2021
A plaque-busting Alzheimer's drug called Aduhelm has yet to prove it can preserve memory and thinking. Even so, its approval by the Food and Drug Administration is making some patients opitimistic.
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NPR
Shots - Health News
Fragile X syndrome involves changes in the X chromosome, as pictured in the four columns of chromosomes starting on the left. The fifth column, on the far right, shows two normal X chromosomes.

An Alzheimer's Drug May Boost Cognition In People With Fragile X Syndrome

Apr 30, 2021
An experimental medicine seems to ease symptoms of Fragile X syndrome, a genetic disorder that is the most common inherited cause of intellectual disabilities and autism.
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NPR
Shots - Health News

Antibody Drugs For COVID-19 Are A Cumbersome Tool Against Surges

Apr 16, 2021
Drugs that can help keep COVID-19 patients out of the hospital are playing only a small role in Michigan, where the pandemic is accelerating. Logistical challenges are to blame.
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NPR
Shots - Health News
A nurse tends to a Covid-19 patient in the intensive care unit at Providence St. Mary Medical Center in Apple Valley, Calif., on Jan. 11.

After A Year Battling COVID-19, Drug Treatments Get A Mixed Report Card

Jan 22, 2021
Drugs for COVID-19 are sorted into three basic categories: They work, they don't work, or there simply isn't enough information to know. A generic steroid is one medicine that proved helpful.
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NPR
Shots - Health News
Sam Berns and Audrey Gordon, executive director of The Progeria Research Foundation and Berns's aunt, attend The New York Premiere Of HBO's "Life According To Sam" on October 8, 2013 in New York City.

FDA Approves First Drug For A Rapid Aging Disorder In Children

Nov 23, 2020
A newly approved drug can extend the lives of children with progeria, a rare disorder that causes rapid aging. The drug is the result of one family's effort to help a child with the fatal condition.
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NPR
Business
Amazon has launched an online pharmacy, sending shares of CVS, Walgreens and Rite Aid tumbling.

Amazon Wants To Sell You Prescription Medications

Nov 17, 2020
Amazon launches an online pharmacy, sending shares of CVS, Walgreens and Rite Aid tumbling. Amazon has pushed to compete with Walmart and major pharmacy chains that have long offered home delivery.
NPR
Shots - Health News
The Food and Drug Administration has authorized Eli Lilly's antibody-based drug bamlanivimab for emergency use as a treatment for COVID-19.

FDA OKs Eli Lilly COVID-19 Drug, But Supplies Will Be Limited

Nov 10, 2020
Eli Lilly's monoclonal antibody will be available to people 65 or older or those with underlying health conditions. Supplies will be short, and allocating the medicine will be a challenge.
NPR
Shots - Health News
Regeneron has developed a drug called REGN-COV2 that is a combination of two monoclonal antibodies that block the virus that causes COVID-19. The company has a contract to supply up to 300 million doses to the U.S. government.

Federal Supply Deal For COVID-19 Antibody Treatment Lacks Some Customary Protections

Nov 06, 2020
To boost the supply of Regeneron's antibody therapy for COVID-19, the federal government entered into a $450 million supply contract. Details of the deal show some safeguards are missing.
NPR
Shots - Health News
Eli Lilly researchers prepare cells to produce possible COVID-19 antibodies in a laboratory in Indianapolis. The drugmaker has asked the U.S. government to allow emergency use of its experimental antibody therapy.

How Will The Limited Supply Of Antibody Drugs For COVID-19 Be Allocated?

Oct 21, 2020
Experimental medicines have the potential to help people with COVID-19 avoid hospitalization. The scarce supply of the treatments would have to be rationed, if regulators OK their use.
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NPR
Shots - Health News
English coronavirus patients George Gilbert, 85, and his wife, Domneva Gilbert, 84, were part of a clinical trial that included Eli Lilly & Co.'s baricitinib.

Experimental Medicines For COVID-19 Could Help Someday, But Home Runs Not Guaranteed

Sep 18, 2020
Drugs are being tested that could reduce symptoms and save lives. But, given the way drugs are developed, it's unlikely that any single medicine will be anywhere as potent as a successful vaccine.
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NPR
Coronavirus Live Updates

COVID-19 Vaccine Trial Paused, Due To Illness In One Volunteer

Sep 08, 2020
A large study of a COVID-19 vaccine candidate has been put on hold after one of the volunteers became ill.
NPR
Coronavirus Live Updates
Director of the National Institutes of Health, Dr. Francis Collins, holds a model of the coronavirus. This is the sixth vaccine candidate to join Operation Warp Speed's portfolio, and the largest vaccine deal to date.

U.S. Reaches $2.1 Billion Deal With Sanofi, GlaxoSmithKline For COVID-19 Vaccine Push

Jul 31, 2020
This is the sixth vaccine candidate to join Operation Warp Speed's portfolio, and the largest vaccine deal to date.
NPR
Coronavirus Live Updates
A bottle of hydroxychloroquine tablets in Texas City, Texas. The Food and Drug Administration has rescinded its emergency use authorization for the drug.

FDA Withdraws Emergency Use Authorization For Hydroxychloroquine

Jun 15, 2020
Emergency use authorization makes it easier for doctors to use a drug in a manner not specifically approved by the Food and Drug Administration. The FDA granted these drugs this status in March.
NPR
The Coronavirus Crisis
An engineer works in April on an experimental COVID-19 vaccine at Sinovac Biotech's facilities in Beijing. Sinovac Biotech is conducting one of four clinical trials that have been authorized in China.

Amid High Stakes, China Is Fast-Tracking COVID-19 Vaccine Efforts

May 20, 2020
Experts say the Communist Party sees more at stake than public health. One of the biggest concerns is the economy. China is also looking to defuse criticism over its early handling of the outbreak.
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NPR
The Coronavirus Crisis
Remarks by Sanofi CEO Paul Hudson provoked an uproar in France this week about access to a future COVID-19 vaccine.

French Drug Giant Sanofi Takes Heat After Suggesting U.S. May Get 1st Vaccine Access

May 15, 2020
An uproar followed comments by Sanofi's CEO that if the company develops a vaccine, doses would likely go to Americans first. The board president later insisted, "Any vaccine will be a public good."
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NPR
Shots - Health News
Stoppers are placed on filled vials of the experimental drug remdesivir at a Gilead Sciences factory.

Remdesivir Distribution Causes Confusion, Leaves Some Hospitals Empty-Handed

May 14, 2020
Gilead Sciences is donating its initial supply of the experimental treatment for COVID-19. The federal government is deciding where the scarce medicine goes, and there are questions about the choices.
NPR
Shots - Health News
Remdesivir, an experimental antiviral drug made by Gilead Sciences, has been authorized by the Food and Drug Administration for emergency use in treating severely ill COVID-19 patients.

Putting A Price On COVID-19 Treatment Remdesivir

May 08, 2020
Gilead Sciences has committed to donating the initial supply of the experimental antiviral drug. But executives said the company will need to make expanded production of the treatment sustainable.
NPR
Shots - Health News
Gilead Sciences CEO Daniel O'Day speaks at a meeting with President Trump and members of the White House coronavirus task force on March 2.

Gilead Lobbying Rose As Interest In COVID-19 Treatment Climbed

May 02, 2020
On Friday, the Food and Drug Administration authorized emergency use of remdesivir for patients with severe cases of COVID-19. Drugmaker Gilead Sciences' lobbying hit a new high in the first quarter.
NPR
Shots - Health News
Only 28% of the factories that make active ingredients for pharmaceuticals for the domestic market are located in the U.S., according to the Food and Drug Administration.

What Would It Take To Bring More Pharmaceutical Manufacturing Back To The U.S.?

Apr 24, 2020
Experts say it could be dangerous to rely on overseas production of medicine in a crisis, but the U.S. largely does. Rebuilding domestic capacity would take years and substantial investments.
NPR
Coronavirus Live Updates
Nurses and health care workers mourn and remember their colleagues who died during the outbreak of the novel coronavirus during a demonstration outside Mount Sinai Hospital in New York.

Coronavirus Vaccine? Two Pharmaceutical Giants Collaborating To Develop One

Apr 14, 2020
Pharmaceutical companies GSK and Sanofi are partnering to work on several vaccine candidates to fight the coronavirus.
NPR
Coronavirus Live Updates
The Food and Drug Administration has authorized two malaria  — chloroquine and hydroxychloroquine — to be added to the national emergency stockpile for use in responding to COVID-19.

FDA OK's Addition To Stockpile Of Malaria Drugs For COVID-19

Mar 30, 2020
Chloroquine and hydroxycloroquine got the Food and Drug Administration's go-ahead to be put in the nation's strategic storehouses. But the drugs haven't been approved to treat coronavirus patients.
NPR
Shots - Health News
Gilead Sciences CEO Daniel O'Day (center) took part in a meeting of the White House Coronavirus Task Force on March 2.

FDA Grants Experimental Coronavirus Drug Benefits For Rare Disease Treatments

Mar 24, 2020
Gilead Science's remdesivir, an antiviral medicine being tested for treatment of COVID-19, would get a seven-year monopoly if approved by the Food and Drug Administration.
NPR
Shots - Health News
Health insurers are limiting which drugs they'll cover, in a bid to limit drug costs.

Insurers Cover Fewer Drugs, Leaving Some Patients Struggling To Get Needed Treatments

Mar 16, 2020
A new report finds insurers are becoming more selective about which medications they'll cover. Patients and doctors have to work harder to get treatments approved.

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