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monoclonal antibodies

NPR
Shots - Health News
Evusheld is a treatment authorized for prevention of COVID-19 in people who are seriously immunocompromised or who have had serious adverse reactions to COVID-19 vaccines.

Hospitals use a lottery to allocate scarce COVID drugs for the immunocompromised

Jan 25, 2022
So far the government has distributed about 300,000 doses of Evusheld, a new drug that protects against COVID-19. Some 7 million Americans could benefit from the drug right away.
NPR
Coronavirus Updates
Florida Gov. Ron DeSantis speaks holding his facemask during a press conference to address the rise of coronavirus cases in the state, at Jackson Memorial Hospital in Miami, on July 13, 2020.

Florida Gov. DeSantis Expands Monoclonal Antibody Treatments Amid COVID-19 Spike

Aug 13, 2021
Monoclonal antibodies can be used to treat people with mild to moderate COVID-19, but the treatment doesn't work for those who've already developed more severe symptoms or are hospitalized.
NPR
Shots - Health News

Antibody Drugs For COVID-19 Are A Cumbersome Tool Against Surges

Apr 16, 2021
Drugs that can help keep COVID-19 patients out of the hospital are playing only a small role in Michigan, where the pandemic is accelerating. Logistical challenges are to blame.
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NPR
Shots - Health News
Deaths from COVID-19 are often due to the immune system overreacting to the coronavirus. New drugs to suppress that reaction are showing promise, say researchers.

Drugs Targeting Immune Response To COVID-19 Show Promise

Apr 07, 2021
Researchers are reporting some progress in their search for drugs that tamp down the overwhelming immune reaction that can kill a patient with COVID-19.
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NPR
Shots - Health News
A nurse tends to a Covid-19 patient in the intensive care unit at Providence St. Mary Medical Center in Apple Valley, Calif., on Jan. 11.

After A Year Battling COVID-19, Drug Treatments Get A Mixed Report Card

Jan 22, 2021
Drugs for COVID-19 are sorted into three basic categories: They work, they don't work, or there simply isn't enough information to know. A generic steroid is one medicine that proved helpful.
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NPR
Shots - Health News
Nurse Salina Padilla prepares an infusion of a COVID-19 antibody treatment at Desert Valley Hospital in Victorville, Calif., in December.

Tracking Down Antibody Treatment Is A Challenge For COVID-19 Patients

Jan 11, 2021
Antibody-based drugs that bind to the coronavirus to prevent it from invading cells can help patients with mild to moderate COVID-19. But the medicines can be tough to find in time.
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NPR
Shots - Health News
Nurse Janet Gilleran prepares to treat COVID-19 patient Mike Mokler with bamlanivimab, a monoclonal antibody drug from Eli Lilly, at the Respiratory Infection Clinic of Tufts Medical Center in Boston on Dec. 31, 2020.

Doctors Encouraged By Antibody Treatments For COVID-19

Jan 06, 2021
While logistical challenges have hampered use of antibody drugs to treat people with mild-to-moderate COVID-19, recent results show the medicines can be worthwhile.
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NPR
Shots - Health News
President Trump boards Marine One for a trip from the White House to Walter Reed National Military Medical Center for COVID-19 treatment in early October. Trump received Regeneron's antibody cocktail during his illness.

Low Demand For Antibody Drugs Against COVID-19

Dec 22, 2020
Monoclonal antibodies to prevent severe COVID-19 aren't being used as widely as expected. Medical staff shortages and patient transportation problems are two of the reasons.
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NPR
Shots - Health News
Regeneron has developed a drug called REGN-COV2 that is a combination of two monoclonal antibodies that block the virus that causes COVID-19. The company has a contract to supply up to 300 million doses to the U.S. government.

Federal Supply Deal For COVID-19 Antibody Treatment Lacks Some Customary Protections

Nov 06, 2020
To boost the supply of Regeneron's antibody therapy for COVID-19, the federal government entered into a $450 million supply contract. Details of the deal show some safeguards are missing.
NPR
Shots - Health News
An Eli Lilly researcher tests possible COVID-19 antibodies in a laboratory in Indianapolis.

Government Signs Deal For COVID-19 Treatments From Eli Lilly

Oct 28, 2020
The federal government plans to distribute 300,000 doses of the drug at no cost, but that doesn't mean treatment will be free. Intravenous infusion charges can run more than $1,000.
NPR
Shots - Health News
Eli Lilly researchers prepare cells to produce possible COVID-19 antibodies in a laboratory in Indianapolis. The drugmaker has asked the U.S. government to allow emergency use of its experimental antibody therapy.

How Will The Limited Supply Of Antibody Drugs For COVID-19 Be Allocated?

Oct 21, 2020
Experimental medicines have the potential to help people with COVID-19 avoid hospitalization. The scarce supply of the treatments would have to be rationed, if regulators OK their use.
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NPR
Shots - Health News
An Eli Lilly researcher tests possible COVID-19 antibodies in a company laboratory in Indianapolis.

Trump Touts Antibody Treatments For COVID-19, But Evidence Is Incomplete

Oct 08, 2020
Medical researchers have high hopes that the kind of treatment the president received could end up being an important element in the fight against the pandemic. But clinical trials continue.
NPR
Shots - Health News
English coronavirus patients George Gilbert, 85, and his wife, Domneva Gilbert, 84, were part of a clinical trial that included Eli Lilly & Co.'s baricitinib.

Experimental Medicines For COVID-19 Could Help Someday, But Home Runs Not Guaranteed

Sep 18, 2020
Drugs are being tested that could reduce symptoms and save lives. But, given the way drugs are developed, it's unlikely that any single medicine will be anywhere as potent as a successful vaccine.
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NPR
Shots - Health News
A researcher at the German Center for Immunity Therapy holds a bag containing blood plasma from a recovered COVID-19 patient at the University Hospital Erlangen on April 27, 2020 in Erlangen, Germany. This plasma could be used to treat people with COVID-

Five Coronavirus Treatments In Development

Jun 11, 2020
While only remdesivir has been scientifically shown to help treat COVID-19, it is not a particularly effective drug. More drugs like it and fundamentally different ones are in the pipeline.
NPR
Shots - Health News
After testing positive for COVID-19, Diana Berrent established Survivor Corps, a grassroots clearinghouse for COVID-19 survivors interested in donating blood plasma to organizations developing therapies that might combat the disease.

Market For Blood Plasma From COVID-19 Survivors Heats Up

May 11, 2020
As many firms and academic researchers vie for blood donations from survivors in hopes of isolating components for new treatments, one project is turning for help from 10,000 Orthodox Jewish women.
NPR
Shots - Health News
Regeneron Pharmaceuticals, headquartered near Tarrytown, N.Y., is just one of the companies now working to identify and reproduce large quantities of antibodies that could prevent or treat COVID-19. Senior R&D Specialist Kristen Pascal works on COVID-19

How Monoclonal Antibodies Might Prove Useful Against The Coronavirus

Mar 26, 2020
A treatment strategy that identifies particularly potent immune system proteins, then gins up mass quantities for a single dose might help prevent infections or quell symptoms, scientists say.
NPR
Shots - Health News
Research & Development associate Divya Nagalati works on cell cultures in Regeneron's infectious disease labs in Tarrytown, N.Y. The firm is looking for tailored antibodies that might prove useful against the new coronavirus.

Hunt For New Coronavirus Treatments Includes Gene-Silencing And Monoclonal Antibodies

Feb 19, 2020
The new coronavirus has spurred biotech labs in universities and companies to try to find new approaches to stopping the virus — from blocking its key enzymes to interfering with its genetics.
NPR
Shots - Health News
In this colorized image of a brain cell from a person with Alzheimer's, the red tangle in the yellow cell body is a toxic tangle of misfolded "tau" proteins, adjacent to the cell's green nucleus.

Alzheimer's Drugs In The Works Might Help Other Diseases, Too

Jul 19, 2015
By targeting the process that creates toxic clumps of protein in brain cells, scientists hope to help not just Alzheimer's patients, but perhaps also people with Lewy Body dementia and Parkinson's.
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