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human embryos

NPR
Shots - Health News
New guidance would ease restrictions on researching embryos in the lab.

Controversial New Guidelines Would Allow Experiments On More Mature Human Embryos

May 26, 2021
An influential scientific society has recommended scrapping a long-standing taboo on studying human embryos in lab dishes beyond 14 days and greenlighted a long list of other sensitive research.
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NPR
Shots - Health News
These human embryo-like structures (top) were synthesized from human stem cells; they've been stained to illustrate different cell types. Images (bottom) of the "embryoids" in the new device that was invented to make them.

Scientists Create A Device That Can Mass-Produce Human Embryoids

Sep 11, 2019
Researchers hope large numbers of very primitive, embryo-like structures will lead to new insights into early human development and ways to prevent miscarriages and birth defects.
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NPR
Shots - Health News
The genetic variation Chinese scientist He Jiankui was trying to re-create when he edited twin girls' DNA may be more harmful than helpful to health overall, a new study says.

2 Chinese Babies With Edited Genes May Face Higher Risk Of Premature Death

Jun 03, 2019
Analysis of DNA from more than 400,000 people in the U.K. suggests a genetic modification that protects against HIV may actually increase the overall risk of premature death.
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NPR
Shots - Health News
As scientists learn more about the complex way genes combine and work together to create human traits, the idea of "designer babies" becomes less and less likely.

Why Making A 'Designer Baby' Would Be Easier Said Than Done

May 02, 2019
Ethical concerns aside, the genetic ingredients for human traits are so complex that editing a few embryonic genes is unlikely to have much effect — or achieve the fantasy of enhancing humans.
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NPR
Shots - Health News
Dieter Egli, a developmental biologist at Columbia University, and Katherine Palmerola examine a newly fertilized egg injected with a CRISPR editing tool.

New U.S. Experiments Aim To Create Gene-Edited Human Embryos

Feb 01, 2019
Despite outrage over gene editing in China that affected the birth of twins, research is underway in the U.S. to assess the safety and effectiveness of CRISPR tools to edit genes in human embryos.
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NPR
Shots - Health News
There has been a backlash since Chinese scientist He Jiankui's claim that he edited genes in embryos that became twin girls.

Outrage Intensifies Over Claims Of Gene-Edited Babies

Dec 07, 2018
Concerns over a Chinese scientist's claim that he created the first gene-edited babies grow with more questions about whether it worked and the possible harm he may have inflicted on the twin girls.
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NPR
The Two-Way
After a cryogenic tank like the one in this file photo lost a great deal of liquid nitrogen, a fertility clinic began the process of determining the damage to stored embryos and eggs.

Fertility Clinic Says Failure May Have Damaged Thousands Of Eggs And Embryos

Mar 12, 2018
The problem hit a San Francisco clinic on March 4 — the same day that a similar cryogenic tank failure was reported in Cleveland.
NPR
Shots - Health News
Niakan says her research is aimed at understanding basic human biology.

Editing Embryo DNA Yields Clues About Early Human Development

Sep 20, 2017
Researchers disabled a gene that they think helps determine which human embryos will develop normally. The technique they used is controversial because it could be used to change babies' DNA.
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NPR
Shots - Health News
Embryoids like this one are created from stem cells and resemble very primitive human embryos. Scientists are studying them in hopes of learning more about basic human biology and development.

Harvard Scientists Call For Better Rules To Guide Research On 'Embryoids'

Mar 21, 2017
Some recent studies in synthetic biology, they say, raise new questions about the ethical limits of creating entities that might feel pain or resemble human embryos — or mimic humans in other ways.
NPR
Shots - Health News
Embryoids like this one are created from stem cells and resemble very primitive human embryos. Scientists hope to use them to learn more about basic human biology and development.

Embryo Experiments Reveal Earliest Human Development, But Stir Ethical Debate

Mar 02, 2017
Researchers who study developing human embryos have long limited their experimentation to lab embryos that are no more than 14 days into development. Some scientists are now pushing that boundary.
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NPR
Shots - Health News
Editing human genes that would be passed on for generations could make sense if the diseases are serious and the right safeguards are in places, a scientific panel says.

Scientific Panel Says Editing Heritable Human Genes Could Be OK In The Future

Feb 14, 2017
The National Academy of Medicine and National Academy of Sciences say a long-standing taboo on editing human genes could be lifted — even if the changes can be carried through to future generations.
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NPR
Shots - Health News
Scientists have the ability to use DNA from three adults to make one embryo. But should they?

Babies With Genes From 3 People Could Be Ethical, Panel Says

Feb 03, 2016
An independent federal panel says the experimental procedure needs to be proven safe, and even then should only be tried with male embryos because of concerns about passing down genetic errors.
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NPR
The Two-Way
Kathy Niakan is leading the Francis Crick Institute research team that applied for permission to edit genes in human embryos.

U.K. Regulator Gives Go-Ahead For Scientists To Edit Genes In Human Embryos

Feb 01, 2016
The researchers want to study the first few days of an embryo's development. They must now seek approval from an ethics committee in the United Kingdom.
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