Life expectancy in the U.S. has taken a significant downward turn. This is especially true in Ohio and West Virginia, which have the highest rates of overdose deaths among people ages 25 to 64.

The federal court decision paves the way for the nation's first supervised injection site to open in Philadelphia. The Justice Department argued that it amounted to "in-your-face illegal activity."

Fatima Suleman, a professor of pharmaceutical sciences, hopes that WHO's Fair Pricing Forum can help lower drug costs — and benefit drug manufacturers.

Prosecutors in 20 states are using old laws to file homicide charges to hold family and friends accountable in opioid-related deaths. The penalty is steep and experts debate its effectiveness.

A new book explores why getting a properly formulated medicine is hit-or-miss in much of the developing world — and why the issue is massively underreported.

Infections from intravenous drug use are often hidden, under sleeves and beneath pants. These wounds of addiction may be buried in shame. They can also be serious, requiring surgery or constant care.

A bill passed by the California Legislature requires drugmakers to give 60 days' notice before raising a drug's price by 16 percent or more over two years, and to justify the price increase.

Manila's cardinal and another senior cleric have harshly criticized what human rights groups call extrajudicial killings that have claimed more than 5,000 lives in the past 14 months.

Coloradans can get arrested for driving while stoned. But with no good roadside tools, officers' determinations are more subjective than for alcohol DUIs. Scientists hope to find chemical markers.

Gustavo Falcon, his brother and their associates were indicted in 1991 for smuggling 75 tons of cocaine into the U.S. His partners were caught and convicted, but Falcon roamed free — until Wednesday.